Toxicology

Toxicology

CEA provide advice and support for all your human health assessment needs. Our expertise is in general chemicals, agrochemicals, biocides, veterinary and human medicines, food additives and cosmetics. We offer support in both hazard and risk assessment. Our particular capabilities are in:

  • Data collation and evaluation
  • Data gap analysis
  • Structure Property/Activity Relationships
  • Read-Across
  • Data provision advice on strategies to minimise/avoid testing
  • Advice on complex study designs and programmes
  • Evaluation and interpretation of tests
  • Management of timely and value-conscious testing programmes
  • Preparation of Robust Summaries in IUCLID
  • Preparation of Chemical Safety Assessments
  • Toxicology product stewardship
  • Leadership in hot topics (e.g. endocrine disruption, nanomaterials, mixtures)
  • Advice on Replacement, Reduction and Refinement approaches
  • Representation on SIEFs and consortia
  • Representation to and liaison with competent authorities, agencies and regulators, including rebuttals

 

Ecotoxicology

CEA provides a full range of Ecotox services to its clients. The services include:

  • Identification of studies needed for regulatory compliance
  • Literature reviews and data searches on specific substances
  • Placing of studies at selected CROs and monitoring of studies to ensure they are compliant
  • Preparation of study summaries, Klimisch evaluations and entry of data into IUCLID 
  • Preparation of study protocols for non-standard ecotox studies and obtaining regulators approval for the non-standard study
  • Calculation of PNEC’s from the study endpoints and assignment of assessment factors
  • Preparation of read-across justifications for REACH registration dossiers

 

Risk assessment

CEA are highly skilled in evaluating the risk of general chemicals to the environment and human health, under REACH. CEA provides expertise reviewing product uses, building exposure scenarios and assessing risks using regulatory accepted models (e.g. ECETOC TRA, CHESAR, ConsExpo). Our experts specialise in higher-tier risk assessments and work closely across ecotoxicology, toxicology and environmental fate to develop realistic exposure assessments.

Meet the Team

Peter Godfrey

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Lincoln Pritchard

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Nathan Brettell

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Alan Lawrence

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Claire McMillan

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Fabienne Ericher

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Theresa Neely

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